Everything about Conolidine alkaloid for chronic pain
Most not too long ago, it's been recognized that conolidine and the above derivatives act to the atypical chemokine receptor three (ACKR3. Expressed in similar areas as classical opioid receptors, it binds into a wide array of endogenous opioids. Unlike most opioid receptors, this receptor functions to be a scavenger and doesn't activate a 2nd mess